Brand Viagra

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Brand Viagra is the most popular drug intended for the treatment of erectile dysfunction in men. This medicine is used to restore sexual reaction and establish an erection mechanism in men.

How does it work?

The active ingredient of the drug is sildenafil citrate, an inhibitor of PDE-5. It prevents the destruction of cGMP, relaxes the smooth muscles of the penis. As a result, the blood flows to the penis and a man is able to get and maintain an erection for a longer time.

Dosage and administration

The drug is taken orally, with a sufficient amount of water. The recommended dose is 50 mg (half of the tablet). If the effect is insufficient – the daily dose can be increased to 100 mg, or vice versa, if the effect is too pronounced and there are side effects – the dose can be reduced to 25 mg. The maximum recommended dose is 100 mg.

Side effects

Brand Viagra is usually well tolerated. In rare cases, it causes mild/moderate side effects: skeletal muscle spasm and increased tone, insomnia, dizziness, headache, fever in the face, pain in the muscles and joints, dyspepsia, diarrhea, nausea, rash, itching, violation of vision clarity, change in color perception, nasal congestion, priapism.

In very rare cases, hearing loss in one ear or loss of vision were recorded in about 500 people out of 23 million patients who used the drug. But it was not possible to prove what really provoked such an extremely uncommon reaction to sildenafil.

Contraindications

Contraindications for Viagra include:

  • individual intolerance to sildenafil and hypersensitivity to any other components of the drugŠ¶
  • violation of blood coagulation;
  • exacerbation of a duodenal ulcer and a stomach ulcer;
  • severe renal and hepatic insufficiency;
  • diseases of the hematopoietic functions (myeloma, sickle cell anemia, leukemia);
  • especially severe forms of hypertension or hypotension, unstable angina, especially dangerous forms of arrhythmia and cardiac safety;
  • a predisposition to priapism;
  • congenital curvature of the penis and fibrosis.
  • recent (up to 6 months) stroke or myocardial infarction;
  • women and children under the age of 18 (due to lack of information on clinical trials);
  • the simultaneous administration of nitrates and nitrogen donors (due to the risk of an instant pressure decrease);
  • pregnancy and breastfeeding.

Overdose

Experiments show an increase in a dosage exceeding the maximum therapeutic dose increases the risk of side effects. In this situation, symptomatic therapy should be used as a treatment. Hemodialysis has no effect because sildenafil actively binds to its proteins once in the bloodstream.

Interaction with other drugs

The simultaneous use of Brand Viagra with cimetidine, erythromycin and ketoconazole may cause a decrease in clearance, as well as an increase in the area under the concentration curve. Co-administration of hypoglycemic drugs, beta-blockers and BMCC is also considered unsafe. Another very dangerous combination is sildenafil and nitrogen donors and other nitrates (due to a possible sharp decrease in blood pressure).

Viagra and alcohol

The combined use of sildenafil with alcohol is not recommended. Patients who have taken alcohol together with Viagra significantly increase the rick of side effects. The most common adverse reaction is a headache. Alcohol also affects the speed and strength of sildenafil’s action, significantly delaying the onset of the effect. Studies of sildenafil at a dose of 50 mg did not confirm that the latter increases the hypertensive or hypotensive effect of alcohol in male volunteers and all indicators were within the arithmetic error.

Advantages of the drug

So, the advantages of Brand Viagra include:

  • hard erection;
  • prolonged sex (the ability to have several sexual intercourses with slight pauses for rest);
  • well-known trusted manufacturer – Pfizer (USA);
  • a minimum number of side effects;
  • positive feedback from doctors and patients.

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